Select the Best Biomarkers
For Researchers who wish to select biomarkers and biomarker levels the most indicative of disease, drug response and efficacy, Entelos simulates and quantifies response to intervention over time across multiple patient cohorts and time points. This can be used to confirm veracity of biomarkers and biomarker levels in diverse patient phenotypes and sub-populations. Thus biosimulation helps to select the optimal biomarkers for different patient types, to optimize assays and to determine measurement schedules.
Questions Biosimulation Can Answer
- Which biomarkers best indicate efficacy for my drug candidate?
- Which biomarkers indicate adverse events for target and candidate mechanisms?
- When should biomarkers be measured to best indicate efficacy and adverse effects?
- Which biomarkers and levels would indicate efficacy in first human trials and the long term?