Entelos and Johnson & Johnson Pharmaceutical Research and Development (J&JPRD) have worked together since 1999 in a broad range of disease areas. J&JPRD collaborated with Entelos to build the Diabetes and Hematopoeisis (anemia) PhysioLab platforms, and Entelos technology and expertise have been applied to a wide variety of projects throughout the entire drug discovery, clinical development, and commercialization pipeline.

Publications:

• Use of Systems Biology in Clinical Development: Design and Prediction of a Type 2 Diabetes Clinical Trial
  PAREXEL Pharmaceutical R&D Sourcebook
  Authors: J. Trimmer, C. McKenna, B. Sudbeck, R. Ho
  2004/2005, p. 131

Press releases:

• Entelos Develops a PhysioLab for Diabetes: Milestone Reached in Partnership with Johnson & Johnson
  June 22, 2001
• The American Diabetes Association Announces the Commencement of the Diabetes Research Forum with Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
  Jan 7, 2003
• Entelos Announces Expansion of Collaboration with Johnson & Johnson Pharmaceutical Research & Development to Include Obesity
  Dec 9, 2003
• Entelos to Develop Hematology Model for Johnson & Johnson Pharmaceutical Research & Development
  Jan 13, 2004
• Entelos Announces Expanded Hematology Collaboration With Johnson & Johnson Pharmaceutical Research & Development
  July 6, 2005
• Entelos Announces Expanded Collaboration with Johnson & Johnson Pharmaceutical Research & Development
  March 16, 2006

• Overview

• ADA Collaboration

• Organon Collaboration

• J&JPRD Collaboration